Risk Assessment for Cronobacter sakazakii in Powdered Infant Formula


Model Summary

The components of the risk assessment model are summarized in the figure below. 

The risk assessment has three main components:

  • Component A addresses the level of C. sakazakii in the PIF at the point of preparation (initial level of contamination).
  • Component B addresses consumption of PIF, estimating the amount of powder consumed per million infant days or per million infants per day.
  • Component C estimates the magnitude of the change in contaminating C. sakazakii (given a contaminated serving) that may occur as a result of preparation, holding and feeding practices. This includes the consideration of growth and inactivation.

These components are combined to give an estimate of the number of cases per million infants per day, which in turn is translated into an estimate of the relative risk enabling a comparison of, for example, different preparation and feeding scenarios compared to a defined baseline scenario.




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